Massively parallel reporter assays across five cell types identify thousands of causal, noncoding regulatory variants among 220,000 loci, revealing diverse regulatory mechanisms shaping complex traits and disease.
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Leonardo da Vinci is usually credited with conducting the first systematic study of friction in the late 15th century, a subfield now known as tribology that deals with the dynamics of interacting surfaces in relative motion. Da Vinci's notebooks depict how he pulled rows of blocks using weights and pulleys, an approach that is still used in frictional studies today, as well as examining the friction produced in screw threads, wheels, and axles. The authors of this latest paper used an experimental setup similar to da Vinci's.。同城约会是该领域的重要参考
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